A brand new examine has discovered that nematode worms grow to be hungrier and like their favorite snacks after consuming hashish, very similar to people. The analysis, printed in Present Biology, found that cannabinoids, the energetic chemical compounds in marijuana, have an effect on Caenorhabditis elegans nematodes in an analogous method to people, regardless of the 2 species evolving down very totally different paths. When the worms’ cannabinoid receptors had been changed with human receptors via genetic engineering, in addition they responded in the identical approach. The findings may assist create medicine that concentrate on the identical receptors.
Cannabinoid receptors have developed to reply to naturally occurring molecules, endocannabinoids, that influence urge for food, nervousness, studying and reminiscence, replica, and metabolism, amongst different issues, in numerous components of the physique, together with the mind and nervous system. A “favoured meals” for nematodes is a particular micro organism. For the examine, two kinds of micro organism had been positioned in a T-shaped maze, with one a superior possibility and the opposite inferior, and the numbers of worms uncovered to cannabinoids at every meals patch over an hour had been counted each quarter-hour. The examine additionally famous how cannabinoids affected the nematodes’ olfactory neurons, which lack cannabinoid receptors.
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Originally posted 2023-04-20 16:14:28.